Carotid Artery Blood Flow Decreases after Rapid Head Rotation in Piglets

  • Clevenger A
  • Kilbaugh T
  • Margulies S
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Abstract Modification of cerebral perfusion pressure and cerebral blood flow (CBF) are crucial components of the therapies designed to reduce secondary damage after traumatic brain injury (TBI). Previously we documented a robust decrease in CBF after rapid sagittal head rotation in our well-validated animal model of diffuse TBI. Mechanisms responsible for this immediate (0.39). The average carotid blood velocity did not differ between sham and injured animals (p=0.91). These data suggest that a reduction in global CBF after rapid sagittal head rotation may be partially mediated by a reduction in carotid artery flow, via vasoconstriction.

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  • Amy C. Clevenger

  • Todd Kilbaugh

  • Susan S. Margulies

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