Journal article

[A case of malignant transformation of gastric hyperplastic polyp with metaplastic bone formation]

Hayashi K, Ohtsuki Y, Sonobe H, Hikita T, Iwata J, Furihata M, Mizobuchi T ...see all

Gan no rinsho Japan journal of cancer clinics, vol. 35, issue 7 (1989) pp. 851-854

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A case of malignant transformation of a gastric hyperplastic polyp with a metaplastic bone formation is reported. A large gastric polyp was revealed by X-ray examination and by endoscopy in the cardia of a 89-year-old female who had complained of nausea. A polypectomy was performed since the biopsied materials had contained some atypical glands intermingled with hyperplastic glands. Histologically, the polyp, 1.7 x 1.0 x 0.6 cm in size, was a hyperplasic polyp that was found to contain superficial dysplastic foci associated with a moderately differentiated type of a tubular adenocarcinoma. A metaplasic bone formation was found in stroma beneath the hyperplastic glandular epithelium. Thus, polypectomy of hyperplastic polyps of the stomach of more than 1 cm with dysplastic foci is recommended.

Author-supplied keywords

  • Adenocarcinoma
  • Aged
  • Aged: 80 and over
  • Bone and Bones
  • Cell Transformation: Neoplastic
  • Female
  • Humans
  • Hyperplasia
  • Metaplasia
  • Polyps
  • Stomach

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  • SCOPUS: 2-s2.0-0024686981
  • PUI: 19443654
  • SGR: 0024686981
  • ISSN: 0021-4949


  • K Hayashi

  • Y Ohtsuki

  • H Sonobe

  • T Hikita

  • J Iwata

  • M Furihata

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