Hypereosinophilic syndrome (HES) is a group of rare blood disorders characterized by a persistent elevation of blood eosinophil count ⩾1.5×109/L and clinical manifestations attributable to eosinophilia or tissue hypereosinophilia. Lymphocytic variant of HES (HES-L) is a known subtype according to World Health Organization classification. It is well documented in the literature that patients with HES-L are predisposed to develop T-cell lymphoma. We report a case of T-cell lymphoproliferation associated with hypereosinophilia, which has been successfully treated with mycophenolate mofetil, with resolution of skin lesions and normalization of eosinophil count and immunoglobulin E level. We believe this is a clinically relevant case since this is a rare disease with little known knowledge on its best treatment modality.
CITATION STYLE
Hanbali, A., Shaheen, M., Alfraih, F., Al-Otaibi, W., El Fakih, R., Owaidah, T., & Ahmed, S. (2018). A case of T-cell lymphoproliferative disorder associated with hypereosinophilia with excellent response to mycophenolate mofetil. Hematology/Oncology and Stem Cell Therapy, 11(4), 241–244. https://doi.org/10.1016/j.hemonc.2016.11.001
Mendeley helps you to discover research relevant for your work.