Cell biology of hydrogels

  • Smetana K
  • 67


    Mendeley users who have this article in their library.
  • 190


    Citations of this article.


This paper demonstrates the hydrophilic polymers (mainly based on hydroxyethyl methacrylate) as a tool of cell biology. They represent a favourable model for the study of the influence of the molecular design of polymers on 1. (1) bioactive protein adsorption, 2. (2) cell adhesion and/or 3. (3) control of their function. The influence of the hydrophilic/hydrophobic properties of polymers and of the occurrence of charged functional chemical groups is able to influence the interaction of cells with these polymers. For example, the copolymer of hydroxyethyl methacrylate with sodium methacrylate (-COO-groups) is only little recognized by macrophages, which could be used in clinical implantology. It is shown that, similar to natural macromolecules of the extracellular matrix, the synthetic polymers are able to participate in the control of cell function. © 1993.

Author-supplied keywords

  • Hydrogels
  • adsorption
  • cell adhesion

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Karel Smetana

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free