Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment

  • Chen J
  • Irianto J
  • Inamdar S
 et al. 
  • 107


    Mendeley users who have this article in their library.
  • 38


    Citations of this article.


This study adopts a combined computational and experimental approach to determine the mechanical, structural, and metabolic properties of isolated chondrocytes cultured within three-dimensional hydrogels. A series of linear elastic and hyperelastic finite-element models demonstrated that chondrocytes cultured for 24 h in gels for which the relaxation modulus is

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • J. Chen

  • J. Irianto

  • S. Inamdar

  • P. Pravincumar

  • D. A. Lee

  • D. L. Bader

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free