Centenarian offspring: Start healthier and stay healthier

  • Adams E
  • Nolan V
  • Andersen S
 et al. 
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OBJECTIVES—To assess the relative incidence of age-related diseases in a group of centenarian offspring who have thus far been considered to be predisposed to “healthy” aging. DESIGN—Longitudinal study. SETTING—Nationwide sample. PARTICIPANTS—Four hundred forty centenarian offspring and 192 referent cohort subjects who met inclusion criteria of having initial and follow-up health questionnaire data available. Median age of both cohorts was 72 at the initial health questionnaire. MEASUREMENTS—Initial health questionnaires were collected from 1997 to 2006. Follow-up questionnaires were collected from 2004 to 2007. The mean period of follow-up was 3.5 ± 1.7 years for the centenarian offspring and 3.9 ± 2.2 years for the referent cohort. RESULTS—During the follow-up period, centenarian offspring had a 78% lower risk of myocardial infarction (P < .04), 83% lower risk of stroke (P

Author-supplied keywords

  • Centenarian
  • Familial
  • Longevity
  • Morbidity

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  • Emily R. Adams

  • Vikki G. Nolan

  • Stacy L. Andersen

  • Thomas T. Perls

  • Dellara F. Terry

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