Changes of attention and memory in a group of patients with multiple sclerosis

  • Janculjak D
  • Mubrin Z
  • Brinar V
 et al. 
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Examined the cognitive performance of patients with multiple sclerosis (MS) on attention and memory-related tasks. The contributions of patients' clinical and demographic characteristics to their cognitive performance were also assessed. 55 inpatients with MS (mean age 33.8 yrs; 24 patients with relapsing-remitting MS, 26 patients with secondary-progressive MS, and 5 patients with undetermined clinical course) were matched with 42 control subjects. All participants completed the Mini-Mental State Examination, a visual sustained attention task, a visual reaction time task, the Sternberg memory scanning paradigm, an implicit learning motor skills task, and motor performance tests. MS patients had a slower reaction time on both tasks that assessed automatic visual information processing. Visual attention task results show a strong association between reaction time and duration of illness, and a weaker association between reaction time and clinical course of the disease. It is concluded that the major cognitive deficit in MS due to demyelination is slowing of the speed of information processing. (PsycINFO Database Record (c) 2002 APA, all rights reserved)

Author-supplied keywords

  • Cognitive Processes
  • Memory
  • Multiple Sclerosis
  • Neurological Disorders & Brain Damage [3297]
  • Reaction Time
  • Sustained Attention
  • attention
  • memory
  • motor performance
  • multiple sclerosis
  • reaction time
  • visual information processing
  • visual sustained

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  • Davor Janculjak

  • Zdenko Mubrin

  • Vesna Brinar

  • George Spilich

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