A chemical epigenetics approach for engineering the in situbiosynthesis of a cryptic natural product from Aspergillus niger

  • Henrikson J
  • Hoover A
  • Joyner P
 et al. 
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A new fungal metabolite, nygerone A (), featuring a unique 1-phenylpyridin-4(1H)-one core that had previously not been reported from any natural source, has been obtained from Aspergillus niger using a chemical epigenetics methodology.

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  • Jon C. Henrikson

  • Ashley R. Hoover

  • P. Matthew Joyner

  • Robert H. Cichewicz

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