Complete hematopoietic chimerism and tolerance of a liver allograft from a deceased male donor developed in a 9-year-old girl, with no evidence of graft-versus-host disease 17 months after transplantation. The tolerance was preceded by a period of severe hemolysis, reflecting partial chimerism that was refractory to standard therapies. The hemolysis resolved after the gradual withdrawal of all immunosuppressive therapy.
CITATION STYLE
Alexander, S. I., Smith, N., Hu, M., Verran, D., Shun, A., Dorney, S., … Stormon, M. O. (2008). Chimerism and Tolerance in a Recipient of a Deceased-Donor Liver Transplant. New England Journal of Medicine, 358(4), 369–374. https://doi.org/10.1056/nejmoa0707255
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