Chimerism and Tolerance in a Recipient of a Deceased-Donor Liver Transplant

  • Alexander S
  • Smith N
  • Hu M
 et al. 
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Abstract

Complete hematopoietic chimerism and tolerance of a liver allograft from a deceased male donor developed in a 9-year-old girl, with no evidence of graft-versus-host disease 17 months after transplantation. The tolerance was preceded by a period of severe hemolysis, reflecting partial chimerism that was refractory to standard therapies. The hemolysis resolved after the gradual withdrawal of all immunosuppressive therapy.

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Authors

  • Stephen I. Alexander

  • Neil Smith

  • Min Hu

  • Deborah Verran

  • Albert Shun

  • Stuart Dorney

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