Clinical application of antithrombogenic hydrogel with long poly (ethylene oxide) chains

  • Nagaoka S
  • Nakao A
  • 13

    Readers

    Mendeley users who have this article in their library.
  • 90

    Citations

    Citations of this article.

Abstract

Thirty clinical tests on PVC drain tubes coated with hydrophilic copolymer with long poly(ethylene oxide) chains (PEO-COAT®) were carried out. Controls were non-coated PVC drain tubes. Thrombogenesis was observed in 24 out of 30 non-coated PVC drain tubes (80%) and in only 4 out of 30 PEO-COAT drain tubes (13%). PEO-COAT drain tubes significantly suppressed absorption of plasma proteins and adhesion of platelets. The excellent antithrombogenic property of this hydrophilic polymer, already suggested by in vitro and in vivo experiments, was demonstrated here clinically. © 1990.

Author-supplied keywords

  • Hydrogels
  • blood compatibility
  • poly(ethylene oxide)

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free