Clinical manifestations of elderly patients with digitalis intoxication in the emergency department

  • Pita-Fernández S
  • Lombardía-Cortiña M
  • Orozco-Veltran D
 et al. 
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Abstract

This study aimed to determine the clinical characteristics of elderly patients diagnosed with digitalis intoxication, on the Emergency Department, University Hospital Complex, A Coruña, Spain. During the study period (January-September 2008) cases were included in which digitalis intoxication was confirmed by plasma digoxin levels. We collected data on age, gender, base-line diseases, therapeutic indications for digoxin, functional classification, ejection fraction, plasma digoxin levels, creatinine clearance, ions, gasometry, electrocardiogram, concomitant medication, symptomatology and treatment. The results were: mean age 82.0±6.6 years, predominantly female subjects (83.7%). The most prevalent pathologies were cardiac valvulopathy (81.0%), hypertension (68.3%) and ischemic cardiopathy (46.3%), 95.1% had a background of cardiac insufficiency, and 52.6% were in functional grade III. The mean digoxin level was 2.7±0.69ng/ml, 23.1% of the patients had a creatinine clearance of less than 60ml/min/1.73m2and 2.6% had a severely reduced glomerular filtration rate (GFR) (clearance

Author-supplied keywords

  • Adverse effects of digitalis
  • Diagnosis of digitalis intoxication
  • Digitalis-treatment
  • Intoxication by digitalis
  • Toxicity of digitalis

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Authors

  • Salvador Pita-Fernández

  • Mónica Lombardía-Cortiña

  • Domingo Orozco-Veltran

  • Vicente Gil-Guillén

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