Clinical outcomes, risk stratification and practice patterns of unstable angina and myocardial infarction without ST elevation: Prospective Registry of Acute Ischaemic Syndromes in the UK (PRAIS-UK)

  • Collinson J
  • Flather M
  • Fox K
 et al. 
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AIMS: To determine characteristics, outcomes, prognostic indicators and management of patients with acute coronary syndromes without ST elevation. METHODS AND RESULTS: A prospective registry was carried out with follow-up for 6 months after index hospital admission. A history of acute cardiac chest pain was required plus ECG changes consistent with myocardial ischaemia and/or prior evidence of coronary heart disease. Patients with ST elevation or those receiving thrombolytic therapy were excluded. A total of 1046 patients were enrolled from 56 U.K. hospitals. The mean age was 66+/-12 years and 39% were female. The rate of death or non-fatal myocardial infarction at 6 months was 12.2% and of death, new myocardial infarction, refractory angina or re-admission for unstable angina at 6 months was 30%. In a multivariate analysis, patients >70 years had a threefold risk of death or new myocardial infarction compared with those

Author-supplied keywords

  • *Physician's Practice Patterns
  • *Registries
  • Acute Disease
  • Aged
  • Angina, Unstable/*mortality/*therapy
  • Arrhythmias, Cardiac
  • Cohort Studies
  • Electrocardiography
  • Female
  • Great Britain/epidemiology
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction/*mortality/*therapy
  • Prospective Studies
  • Risk Factors
  • Survival Analysis
  • Syndrome

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  • J Collinson

  • M D Flather

  • K A Fox

  • I Findlay

  • E Rodrigues

  • P Dooley

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