Clinical outcomes, risk stratification and practice patterns of unstable angina and myocardial infarction without ST elevation: Prospective Registry of Acute Ischaemic Syndromes in the UK (PRAIS-UK).

  • J. C
  • M.D. F
  • K.A.A. F
 et al. 
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Abstract

AIMS: To determine characteristics, outcomes, prognostic indicators and management of patients with acute coronary syndromes without ST elevation., METHODS AND RESULTS: A prospective registry was carried out with follow-up for 6 months after index hospital admission. A history of acute cardiac chest pain was required plus ECG changes consistent with myocardial ischaemia and/or prior evidence of coronary heart disease. Patients with ST elevation or those receiving thrombolytic therapy were excluded. A total of 1046 patients were enrolled from 56 U.K. hospitals. The mean age was 66+/-12 years and 39% were female. The rate of death or non-fatal myocardial infarction at 6 months was 12.2% and of death, new myocardial infarction, refractory angina or re-admission for unstable angina at 6 months was 30%. In a multivariate analysis, patients >70 years had a threefold risk of death or new myocardial infarction compared with those

Author-supplied keywords

  • *Angina
  • *Myocardial Infarction/mo [Mortality]
  • *Myocardial Infarction/th [Therapy]
  • *Practice Patterns
  • *Registries
  • *ST segment elevation
  • *heart infarction/di [Diagnosis]
  • *heart infarction/dt [Drug Therapy]
  • *heart infarction/ep [Epidemiology]
  • *heart infarction/et [Etiology]
  • *ischemic heart disease/di [Diagnosis]
  • *ischemic heart disease/dt [Drug Therapy]
  • *ischemic heart disease/ep [Epidemiology]
  • *ischemic heart disease/et [Etiology]
  • *register
  • *unstable angina pectoris/di [Diagnosis]
  • *unstable angina pectoris/dt [Drug Therapy]
  • *unstable angina pectoris/ep [Epidemiology]
  • *unstable angina pectoris/et [Etiology]
  • Acute Disease
  • Aged
  • Arrhythmias
  • Cardiac
  • Cohort Studies
  • Electrocardiography
  • Female
  • Great Britain/ep [Epidemiology]
  • Humans
  • Male
  • Middle Aged
  • Physicians'
  • Prospective Studies
  • Risk Factors
  • Survival Analysis
  • Syndrome
  • United Kingdom
  • Unstable/mo [Mortality]
  • Unstable/th [Therapy]
  • acetylsalicylic acid/dt [Drug Therapy]
  • acetylsalicylic acid/pd [Pharmacology]
  • acetylsalicylic acid/po [Oral Drug Administration]
  • adult
  • aged
  • angiography
  • antilipemic agent/dt [Drug Therapy]
  • antilipemic agent/pd [Pharmacology]
  • article
  • beta adrenergic receptor blocking agent/dt [Drug T
  • beta adrenergic receptor blocking agent/pd [Pharma
  • beta adrenergic receptor blocking agent/po [Oral D
  • calcium antagonist/dt [Drug Therapy]
  • calcium antagonist/pd [Pharmacology]
  • calcium antagonist/po [Oral Drug Administration]
  • clinical trial
  • cohort analysis
  • controlled clinical trial
  • controlled study
  • electrocardiography monitoring
  • female
  • fibrinolytic agent/dt [Drug Therapy]
  • fibrinolytic agent/pd [Pharmacology]
  • heparin/dt [Drug Therapy]
  • heparin/iv [Intravenous Drug Administration]
  • heparin/pd [Pharmacology]
  • human
  • major clinical study
  • male
  • morbidity
  • mortality
  • multivariate analysis
  • nitrate/bd [Buccal Drug Administration]
  • nitrate/dt [Drug Therapy]
  • nitrate/iv [Intravenous Drug Administration]
  • nitrate/pd [Pharmacology]
  • nitrate/po [Oral Drug Administration]
  • nitrate/tp [Topical Drug Administration]
  • potassium channel stimulating agent/dt [Drug Thera
  • potassium channel stimulating agent/pd [Pharmacolo
  • potassium channel stimulating agent/po [Oral Drug
  • priority journal
  • prognosis
  • prospective study
  • risk assessment
  • statin/dt [Drug Therapy]
  • statin/pd [Pharmacology]
  • thorax pain/ep [Epidemiology]
  • thorax pain/et [Etiology]
  • treatment outcome

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Authors

  • Collinson J.

  • Flather M.D.

  • Fox K.A.A.

  • Findlay I.

  • Rodrigues E.

  • Dooley P.

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