A clinical perspective of rheumatoid arthritis

  • Scherer H
  • Burmester G
  • 16


    Mendeley users who have this article in their library.
  • 5


    Citations of this article.


In recent years, factors potentially involved in pathogenesis of rheumatoid arthritis have mostly been identified by studying well-defined patient cohorts. Characterization of antibodies from sera of affected patients, family-based heritability studies, genome-wide association scans, the analysis of environmental factors and data from clinical trials have contributed largely to a thorough reassembly of our perception of rheumatoid arthritis. Modified animal models are now crucial to obtain experimental evidence for suggested pathogenetic pathways based on these observations and are currently being developed and explored. Some of the novel pathogenetic aspects, however, already influence decision making in the clinic.

Author-supplied keywords

  • Anti-citrullinated protein antibodies
  • Anti-mutated isoforms of citrullinated vimentin
  • Rheumatoid arthritis
  • Undifferentiated arthritis

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free