Clinical significance of the genetic landscape of pancreatic cancer and implications for identification of potential long-term survivors

  • Yachida S
  • White C
  • Naito Y
 et al. 
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Abstract

Genetic alterations of KRAS, CDKN2A, TP53, and SMAD4 are the most frequent events in pancreatic cancer. We determined the extent to which these 4 alterations are coexistent in the same carcinoma, and their impact on patient outcome.

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Authors

  • Shinichi Yachida

  • Catherine M. White

  • Yoshiki Naito

  • Yi Zhong

  • Jacqueline A. Brosnan

  • Anne M. Macgregor-Das

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