Cochlear implantation for chronic electrical stimulation in the mouse

  • Irving S
  • Trotter M
  • Fallon J
 et al. 
  • 28

    Readers

    Mendeley users who have this article in their library.
  • 6

    Citations

    Citations of this article.

Abstract

The mouse is becoming an increasingly attractive model for auditory research due to the number of genetic deafness models available. These genetic models offer the researcher an array of congenital causes of hearing impairment, and are therefore of high clinical relevance. To date, the use of mice in cochlear implant research has not been possible due to the lack of an intracochlear electrode array and stimulator small enough for murine use, coupled with the difficulty of the surgery in this species. Here, we present a fully-implantable intracochlear electrode stimulator assembly designed for chronic implantation in the mouse. We describe the surgical approach for implantation, as well as presenting the first functional data obtained from intracochlear electrical stimulation in the mouse. © 2013 Elsevier B.V.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • S. Irving

  • M. I. Trotter

  • J. B. Fallon

  • R. E. Millard

  • R. K. Shepherd

  • A. K. Wise

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free