Cofactor biosynthesis: a mechanistic perspective

  • Begley T
  • Kinsland C
  • Taylor S
 et al. 
  • 14


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


A review, with 217 refs. The chem. of the cofactors has provided a fertile area of overlap between org. chem. and biochem., and the org. chem. of the cofactors is now a thoroughly studied area. In contrast, the chem. of cofactor biosynthesis is still relatively underdeveloped. In this review the biosynthesis of NAD, riboflavin, folate, molybdopterin, thiamin, biotin, lipoic acid, pantothenic acid, CoA, S-adenosylmethionine, pyridoxal phosphate, ubiquinone and menaquinone in E. coli will be described with a focus on unsolved mechanistic problems. [on SciFinder (R)]

Author-supplied keywords

  • Coenzymes
  • Escherichia cofactor biosynthesis review
  • Escherichia coli (Escherichia coli cofactor biosyn
  • Ubiquinones Role: BSU (Biological study, unclassif
  • review cofactor biosynthesis mechanism

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Tadhg P Begley

  • Cynthia Kinsland

  • Sean Taylor

  • Manish Tandon

  • Robb Nicewonger

  • Min Wu

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free