Comparison of the effects of intra-articular injections of hyaluronan and its chemically cross-linked derivative (Hylan G-F20) in normal rabbit knee joints

  • Schiavinato A
  • Finesso M
  • Cortivo R
 et al. 
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Intraarticular injection of native hyaluronan (HA) or a cross-linked derivative are commonly utilized in the treatment of osteoarthritis. Unlike from native hyaluronan, the crosslinked HA derivative is a gel containing also other chemical entities. This study compares the local tolerability of these different preparations in normal rabbit knees, in order to provide further information on their biological effects.

Author-supplied keywords

  • Artz??
  • Eosinophils
  • Hyalgan??
  • Hylan G-F 20 (Synvisc??)
  • Synovial fluid
  • Synovial membrane

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  • ISSN: 0392856X
  • PMID: 12175098
  • PUI: 34846617
  • ISBN: 0392-856X
  • SGR: 0035988597
  • SCOPUS: 2-s2.0-0035988597


  • A. Schiavinato

  • M. Finesso

  • R. Cortivo

  • G. Abatangelo

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