Congenitally bicuspid aortic valves: A surgical pathology study of 542 cases (1991 through 1996) and a literature review of 2,715 additional cases

  • Sabet H
  • Edwards W
  • Tazelaar H
 et al. 
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Objective: To describe a clinicopathologic study of a large group of congenitally bicuspid aortic valves surgically excised at a single institution. Material and Methods: The medical charts and bicuspid valves from patients undergoing aortic valve replacement at Mayo Clinic Rochester between 1991 and 1996 were retrospectively reviewed. Results: The age of the 542 patients ranged from 1 to 86 years (mean, 61), and 372 (69%) were men. Among these, 409 (75%) had pure aortic stenosis (AS), 73 (13%) had pure aortic insufficiency (regurgitation) (AI), 53 (10%) had combined AS and AI, and 7 (1%) had normal function. The mean age was higher for those with AS than AI (65 versus 46 years; P

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  • Haideh Yazdani Sabet

  • William D. Edwards

  • Henry D. Tazelaar

  • Richard C. Daly

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