Conjugated polymer nanoparticles for small interfering RNA delivery.

  • Moon J
  • Mendez E
  • Kim Y
 et al. 
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Abstract

Loosely aggregated conjugated polymer nanoparticles (CPNs) were used as nontoxic and efficient small interfering RNA (siRNA) delivery vehicles with delivery visualization. A significant down regulation (94%) of a target gene was achieved by transfection of HeLa cells with the CPNs/siRNA complexes, supporting CPN as a promising siRNA delivery carrier. [on SciFinder(R)]

Author-supplied keywords

  • conjugate polymer nanoparticle interfering RNA

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Authors

  • Joong Ho Moon

  • Eladio Mendez

  • Yong Kim

  • Aman. Kaur

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