Continuing clozapine treatment despite neutropenia

  • Esposito D
  • Rouillon F
  • Limosin F
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Abstract

Approximately 1-2% of patients treated with the atypical antipsychotic clozapine develop severe neutropenia and agranulocytosis. The usual recommendation is to discontinue treatment with the drug when the peripheral neutrophil count drops below 1,500/mm3.

Author-supplied keywords

  • Agranulocytosis
  • Clozapine
  • Granulopoiesis-stimulating factors
  • Lithium
  • Neutropenia

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Authors

  • David Esposito

  • Frédéric Rouillon

  • Frédéric Limosin

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