Copper(I) carboxylate catalyzed C-N coupling of 2-amino pyrimidines with aryl halides to selectively generate secondary and tertiary amines

  • Zhang Y
  • Quan Z
  • Gong H
 et al. 
  • 4

    Readers

    Mendeley users who have this article in their library.
  • 7

    Citations

    Citations of this article.

Abstract

(2-Chlorobenzoyloxy)copper(I) exhibited high activity towards the challenging amination of 2-amino pyrimidines with aryl halides. Herein, secondary and tertiary amines were selectively produced by using potassium phosphate and sodium-t-butoxide. Potassium phosphate favored the formation of secondary amines, whereas tertiary amines were favored when sodium-t-butoxide was used.

Author-supplied keywords

  • 2-Aminopyrimidines
  • Amination
  • Cu(I)-catalyst
  • Secondary amines
  • Tertiary amines

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Yue Zhang

  • Zheng Jun Quan

  • Hai Peng Gong

  • Yu Xia Da

  • Zhang Zhang

  • Xi Cun Wang

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free