Copper-Mediated Synthesis of N-Acyl Vinylogous Carbamic Acids and Derivatives: Synthesis of the Antibiotic CJ-15,801

  • Han C
  • Shen R
  • Su S
 et al. 
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Abstract

[reaction: see text] Copper(I)-mediated C-N bond formation has been employed to prepare both N-acyl vinylogous carbamic acids and ureas. The novel N-acyl vinylogous carbamic acid antibiotic, CJ-15,801, was synthesized using this methodology.

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Authors

  • Chong Han

  • Ruichao Shen

  • Shun Su

  • John A. Porco

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