OPINION STATEMENT: Fractional flow reserve (FFR) is an invasive pressure-derived index of epicardial stenosis severity used in the catheterization laboratory to assess the hemodynamic significance of coronary lesions when non-invasive functional assessment has either not been performed or is inconclusive. The rationale for the use of FFR is that coronary angiography cannot accurately predict the hemodynamic significance of lesions with diameter stenosis 0.80. Use of FFR to direct coronary revascularization should continue to increase as it has been demonstrated to improve outcomes and reduce cost.
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