Corpus callosum and cingulum tractography in Parkinson's disease

  • Wiltshire K
  • Concha L
  • Gee M
 et al. 
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Abstract

In Parkinson's disease (PD) cell loss in the substantia nigra is known to result in motor symptoms; however widespread pathological changes occur and may be associated with non-motor symptoms such as cognitive impairment. Diffusion tensor imaging is a quantitative imaging method sensitive to the micro-structure of white matter tracts.

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