Critical review and uncertainty analysis of factors influencing influenza transmission

  • Jones R
  • 3


    Mendeley users who have this article in their library.
  • 12


    Citations of this article.


Influenza remains a significant threat to public health, yet there is significant uncertainty about the routes of influenza transmission from an infectious source through the environ- ment to a receptor, and their relative risks. Herein, data pertaining to factors that influence the environmental mediation of influenza transmission are critically reviewed, including: fre- quency, magnitude and size distribution and virus expiration, inactivation rates, environmen- tal and self-contact rates, and viral transfer efficiencies during contacts.Where appropriate, two-stage Monte Carlo uncertainty analysis is used to characterize variability and uncertainty in the reported data. Significant uncertainties are present in most factors, due to: limitations in instrumentation or study realism; lack of documentation of data variability; or lack of study. These analyses, and future experimental work, will improve parameterization of influenza transmission and risk models, facilitating more robust characterization of the magnitude and uncertainty in infection risk.

Author-supplied keywords

  • Contact rates
  • Environmental mediation
  • Inactivation rate
  • Influenza
  • Transfer efficiency

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • Rachael M. Jones

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free