Use of cyclodextrins in topical formulations: Practical aspects

  • Cal K
  • Centkowska K
  • 83

    Readers

    Mendeley users who have this article in their library.
  • 85

    Citations

    Citations of this article.

Abstract

Cyclodextrins are promising, but using them as an excipients can sometimes be difficult. The aim of this review is to summarize the results of recent studies on the application of parent cyclodextrins (??-, ??-, ??-) and some of their derivatives in topical formulations. General properties, current legal status, and toxicological aspects of cyclodextrins are briefly described. The goal of using cyclodextrins to create new formulations with well-known actives, advantages, and limitations in topical formulations is presented, and possible applications in such preparations are also discussed. ?? 2007 Elsevier B.V. All rights reserved.

Author-supplied keywords

  • Cyclodextrins
  • Mucosal delivery
  • Ocular delivery
  • Skin penetration
  • Topical preparations
  • Toxicity

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Krzysztof Cal

  • Katarzyna Centkowska

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free