Journal article

Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study

Pereira M, Jacobs D, Van Horn L, Slattery M, Kartashov A, Ludwig D ...see all

Journal of the American Medical Association, vol. 287, issue 16 (2002) pp. 2081-2089

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Abstract

CONTEXT: Components of the insulin resistance syndrome (IRS), including obesity, glucose intolerance, hypertension, and dyslipidemia, are major risk factors for type 2 diabetes and heart disease. Although diet has been postulated to influence IRS, the independent effects of dairy consumption on development of this syndrome have not been investigated. OBJECTIVE: To examine associations between dairy intake and incidence of IRS, adjusting for confounding lifestyle and dietary factors. DESIGN: The Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based prospective study. SETTING AND PARTICIPANTS: General community sample from 4 US metropolitan areas of 3157 black and white adults aged 18 to 30 years who were followed up from 1985-1986 to 1995-1996. MAIN OUTCOME MEASURE: Ten-year cumulative incidence of IRS and its association with dairy consumption, measured by diet history interview. RESULTS: Dairy consumption was inversely associated with the incidence of all IRS components among individuals who were overweight (body mass index > or =25 kg/m(2)) at baseline but not among leaner individuals (body mass index < 25 kg/m(2)). The adjusted odds of developing IRS (2 or more components) were 72% lower (odds ratio, 0.28; 95% confidence interval, 0.14-0.58) among overweight individuals in the highest (> or =35 times per week, 24/102 individuals) compared with the lowest (

Author-supplied keywords

  • Adult
  • Aged
  • Arteries
  • Body Mass Index
  • Cardiovascular Diseases
  • Dairy Products
  • Disease
  • Glucose Intolerance
  • Hypertension
  • Incidence
  • Life Style
  • Logistic Models
  • Metabolic Syndrome X
  • Odds Ratio
  • Overweight
  • Prospective Studies
  • Risk
  • Risk Factors
  • Syndrome
  • baseline
  • cardiovascular
  • children
  • complications
  • development
  • diabetes
  • diet
  • epidemiology
  • glucose
  • heart
  • history
  • human
  • insulin
  • insulin resistance
  • obesity

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  • PMID: 11966382

Authors

  • M A Pereira

  • D R Jacobs

  • L Van Horn

  • M L Slattery

  • A I Kartashov

  • D S Ludwig

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