Decreasing sleep-time blood pressure determined by ambulatory monitoring reduces cardiovascular risk

  • Hermida R
  • Ayala D
  • Mojón A
 et al. 
  • 86


    Mendeley users who have this article in their library.
  • 155


    Citations of this article.


Objectives: We investigated whether reduced cardiovascular risk is more related to the progressive decrease of asleep or awake blood pressure. Background: Independent studies have concluded that elevated sleep-time blood pressure is a better predictor of cardiovascular risk than awake or 24-h blood pressure means. However, the impact on cardiovascular risk of changes in these ambulatory blood pressure characteristics has not been properly investigated. Methods: We prospectively studied 3,344 subjects (1,718 men and 1,626 women), 52.6 ± 14.5 years of age, during a median follow-up of 5.6 years. Those with hypertension at baseline were randomized to ingest all their prescribed hypertension medications upon awakening or

Author-supplied keywords

  • ambulatory blood pressure monitoring
  • cardiovascular risk
  • chronotherapy
  • hypertension
  • sleep-time relative blood pressure decline

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • Ramón C. Hermida

  • Diana E. Ayala

  • Artemio Mojón

  • José R. Fernández

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free