Delayed intravenous contrast-enhanced 3D FLAIR MRI in Meniere's disease: Correlation of quantitative measures of endolymphatic hydrops with hearing

  • Sepahdari A
  • Ishiyama G
  • Vorasubin N
 et al. 
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Objective: Using three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI), our goal was to correlate quantifiable measures of endolymphatic hydrops (EH) with auditory function in the setting of Meniere's disease (MD). Materials and methods: Forty-one ears were analyzed in 21 subjects (12 ears with MD, 29 without MD). Vestibular endolymphatic space size measurements obtained with two different techniques were referenced against clinical data. Results: EH was better evaluated on 3D maximum intensity projections (MIPs) than on two-dimensional (2D) images. Using MIPs, quantitative assessments EH correlated with severity of hearing impairment. Conclusion: 3D MIPs were superior to 2D images for evaluating EH in the setting of MD.

Author-supplied keywords

  • 3D FLAIR
  • Endolymphatic hydrops
  • Inner ear
  • Meniere's disease

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  • Ali SepahdariUniversity of California - Los Angeles

  • Gail Ishiyama

  • Nopawan Vorasubin

  • Kevin A. Peng

  • Michael Linetsky

  • Akira Ishiyama

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