Depression, anxiety, and quality of life in patients with epithelial ovarian cancer

  • Bodurka-Bevers D
  • Basen-Engquist K
  • Carmack C
 et al. 
  • 1


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


OBJECTIVE: The aims of this study were to evaluate psychological distress and quality of life (QOL) in patients with epithelial ovarian cancer (EOC) and to examine the relationship between these problems and health and demographic variables. METHODS: Of 344 consecutive patients identified, 246 completed questionnaires. Four dimensions of QOL were assessed including physical, functional, emotional, and social/family well-being, as well as concerns specific to ovarian cancer patients. Depression was measured with the Center for Epidemiologic Studies-Depression (CES-D) scale and anxiety was measured by the State Anxiety Subscale of the Spielberger State-Trait Anxiety Inventory. Performance status was evaluated by the Zubrod score. RESULTS: Sixty-five patients (26%) had early stage disease; 181 (74%) had advanced disease. One hundred twenty-one patients (49%) were under active treatment, while 124 (51%) were seen for posttherapy surveillance. Forty-eight (21%) met CES-D cutoff criteria for a clinical evaluation for depression, and 29% scored above the 75th percentile for anxiety. Performance status was related to depression, anxiety, and QOL problems, except in the domain of social well-being. CONCLUSIONS: Clinically significant depression and anxiety may be more prevalent in patients with EOC than previously reported. Future studies of screening for and treating psychological distress are being designed to improve QOL in these women

Author-supplied keywords

  • Active
  • Adult
  • Aged
  • Anxiety
  • Cancer
  • Depression
  • Disease
  • Epithelial Cells
  • Female
  • Health
  • Human
  • Life
  • Middle Age
  • Neoplasm Staging
  • Ovarian Neoplasms
  • Patients
  • Prevalence
  • Psychological
  • Quality of Life
  • Questionnaires
  • Regression Analysis
  • Severity of Illness Index
  • Social
  • Texas
  • Women
  • epidemiology
  • etiology
  • hoofdstuk 7
  • methods
  • pathology
  • psychology
  • therapy
  • treatment

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

There are no full text links


Error loading document authors.

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free