The article focuses on methodic of design plant layout and possibilities of interconnection used software tools. It is generated a simulation model from a common database. By subsequent dynamic simulation experimentation it is gained layout information in term of flowing time and influences of uncertainties. These data are used in layout design managed by CAD system. The solving of facilities disposition is influenced by real spatial constraints and also constraints obtained from the simulation. That enables design of so called dynamic layout meaning flexible and robust one against stochastic influences.
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