Detection of Rabies Virus Antibodies in Fruit Bats (Eidolon helvum) from Nigeria

  • Aghomo H
  • Ako-Nai A
  • Oduye O
 et al. 
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Abstract

Fruit bats (Eidolon helvum) were collected from three different localities in Western Nigeria: Oti, Ibadan and Idanre. Fifty serum samples were analyzed using a modified rapid fluorescent focus inhibition technique against rabies, Mokola, Lagos bat and Duvenhage viruses. Twenty-five brain samples were screened for rabies and related lyssavirus antigens by direct fluorescent antibody microscopy and by an indirect fluorescent antibody technique with rabies anti-nucleocapsid monoclonal antibodies. All brain samples were negative. Two serum samples had relatively high anti-rabies activity; no neutralizing activity was detected against Mokola, Lagos bat or Duvenhage viruses.

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Authors

  • Helen O. Aghomo

  • Ajibade K. Ako-Nai

  • Oladipo O. Oduye

  • Oyewale Tomori

  • Charles E. Rupprecht

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