Development of monocytes, macrophages, and dendritic cells

  • Geissmann F
  • Manz M
  • Jung S
 et al. 
  • 354

    Readers

    Mendeley users who have this article in their library.
  • 1.4k

    Citations

    Citations of this article.

Abstract

Monocytes and macrophages are critical effectors and regulators of inflammation and the innate immune response, the immediate, pre-programmed arm of the immune system. Dendritic cells initiate and regulate the highly pathogen-specific adaptive immune responses, and are central to the development of immunologic memory and tolerance. Recent in vivo experimental approaches in the mouse have unveiled new aspects of the developmental and lineage relationships among these cell populations. Despite this, the origin and differentiation cues for many tissue macrophages, monocytes, and dendritic cell subsets in mice, and the corresponding cell populations in humans, remain to be elucidated

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Frederic Geissmann

  • Markus G. Manz

  • Steffen Jung

  • Michael H. Sieweke

  • Miriam Merad

  • Klaus Ley

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free