Dextran-linked insulin: A soluble high molecular weight derivative with biological activity invivo and invitro

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Abstract

Insulin has been covalently linked to dextran, mw 2,000,000. The soluble derivative has intrinsic biological activity in lowering blood glucose levels invivo and in glucose uptake in isolated fat cells invitro. © 1972.

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Armstrong, K. J., Noall, M. W., & Stouffer, J. E. (1972). Dextran-linked insulin: A soluble high molecular weight derivative with biological activity invivo and invitro. Biochemical and Biophysical Research Communications, 47(2), 354–360. https://doi.org/10.1016/0006-291X(72)90720-6

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