Use of diuretics during pregnancy

  • Al-Balas M
  • Bozzo P
  • Einarson A
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QUESTION: Several of my pregnant patients use diuretics for hypertension. I have heard that diuretics cannot be used in pregnancy because of the reduction of plasma volume and the potential for decreasing placental perfusion, as well as a possible diabetogenic effect.

ANSWER: Many studies--including a meta-analysis of almost 7000 neonates exposed to diuretics during pregnancy--did not find an increased risk of adverse effects, such as birth defects, fetal growth restriction, thrombocytopenia, or diabetes, among neonates exposed to diuretics in utero.

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  • Mosa'b Al-Balas

  • Pina Bozzo

  • Adrienne Einarson

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