DNA ends: Maintenance of chromosome termini versus repair of double strand breaks

  • Lundblad V
  • 32


    Mendeley users who have this article in their library.
  • 61


    Citations of this article.


This review focuses on the factors that define the differences between the two types of DNA ends encountered by eukaryotic cells: telomeres and double strand breaks (DSBs). Although these two types of DNA termini are functionally distinct, recent studies have shown that a number of proteins is shared at telomeres and sites of DSB repair. The significance of these common components is discussed, as well as the types of DNA repair events that can compensate for a defective telomere. Copyright (C) 2000 Elsevier Science B.V.

Author-supplied keywords

  • ALT mechanism
  • DNA repair
  • Double strand breaks
  • Survivor pathway
  • Telomeres

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Victoria Lundblad

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free