DNA micelle flares for intracellular mrna imaging and gene therapy

  • Chen T
  • Wu C
  • Jimenez E
 et al. 
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Lighting the way with DNA: Molecular beacon micelle flares (MBMFs), based on self-assembly of diacyllipid-molecular-beacon conjugates (L-MBs; see figure), have been developed for combined mRNA detection and gene therapy. These MBMFs were shown to inhibit a model gene in vitro and decrease the viability of cancer cells in culture.

Author-supplied keywords

  • DNA micelles
  • RNA recognition
  • gene therapy
  • mRNA imaging
  • self-assembly

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  • Tao Chen

  • Cuichen Sam Wu

  • Elizabeth Jimenez

  • Zhi Zhu

  • Joshua G. Dajac

  • Mingxu You

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