DNA sensing by field-effect transistors based on networks of carbon nanotubes

  • Gui E
  • Li L
  • Zhang K
 et al. 
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Abstract

We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.

Author-supplied keywords

  • Biosensing Techniques/instrumentation/*methods
  • Chromium/chemistry
  • DNA Probes/*chemistry
  • Electrochemistry
  • Electrodes
  • Gold/chemistry
  • In Situ Hybridization/instrumentation/*methods
  • Microscopy, Fluorescence
  • Nanotubes, Carbon/*chemistry
  • Spectrum Analysis, Raman
  • Transistors, Electronic

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Authors

  • E L Gui

  • L J Li

  • K Zhang

  • Y Xu

  • X Dong

  • X Ho

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