Dynamic protein methylation in chromatin biology

159Citations
Citations of this article
301Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Post-translational modification of chromatin is emerging as an increasingly important regulator of chromosomal processes. In particular, histone lysine and arginine methylation play important roles in regulating transcription, maintaining genomic integrity, and contributing to epigenetic memory. Recently, the use of new approaches to analyse histone methylation, the generation of genetic model systems, and the ability to interrogate genome wide histone modification profiles has aided in defining how histone methylation contributes to these processes. Here we focus on the recent advances in our understanding of the histone methylation system and examine how dynamic histone methylation contributes to normal cellular function in mammals. © 2008 Birkhäuser Verlag.

Cite

CITATION STYLE

APA

Ng, S. S., Yue, W. W., Oppermann, U., & Klose, R. J. (2009, February). Dynamic protein methylation in chromatin biology. Cellular and Molecular Life Sciences. https://doi.org/10.1007/s00018-008-8303-z

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free