Early Enteral Nutrition and Clinical Outcomes of Severe Traumatic Brain Injury Patients in Acute Stage: A Multi-Center Cohort Study

  • Chiang Y
  • Chao D
  • Chu S
 et al. 
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Abstract

Abstract Guidelines for patients with severe traumatic brain injury (sTBI) published in 2007 recommend providing early nutrition after trauma. Early enteral nutrition (EN) started within 48 h post-injury reduces clinical malnutrition, prevents bacterial translocation from the gastrointestinal tract, and improves outcome in sTBI patients sustaining hypermetabolism and hypercatabolism. The aim of this study was to examine the effect of early EN support on survival rate, Glasgow Coma Scale (GCS) score, and clinical outcome of sTBI patients. Medical records of sTBI patients with GCS scores 4–8 were recruited from 18 hospitals in Taiwan, excluding patients with GCS scores ≤3. During 2002–2010, data from 145 EN patients receiving appropriate calories and nutrients within 48 h post-trauma were collected and compared with 152 non-EN controls matched for gender, age, body weight, initial GCS score, and operative status. The EN patients had a greater survival rate and GCS score on the 7th day in the intensive care ...

Author-supplied keywords

  • GCS
  • early enteral feeding
  • initial severity
  • sTBI
  • survival rate

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Authors

  • Yung-Hsiao Chiang

  • Dan-Ping Chao

  • Shu-Fen Chu

  • Hui-Wen Lin

  • Shih-Yi Huang

  • Yi-Shian Yeh

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