Early intervention of recent onset mild persistent asthma in children aged under 11 yrs: The Steroid Treatment As Regular Therapy in early asthma (START) trial

  • Chen Y
  • Busse W
  • Pedersen S
 et al. 
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Inhaled corticosteroids are known to be effective in persistent asthma, but their long-term effect in mild persistent disease of recent onset, which is particularly relevant in children, requires clarification. The objective of this study was to determine the long-term efficacy of regular inhaled low-dose budesonide in children aged 2-agonists. Budesonide treatment also had a significant beneficial effect on lung function relative to placebo. In conclusion, early intervention adding once-daily budesonide to usual care in children with mild, persistent asthma of recent onset reduces the long-term risk and frequency of SAREs and improves lung function compared with usual care alone. copyright 2006 Blackwell Munksgaard.

Author-supplied keywords

  • Asthma
  • Budesonide
  • Early intervention
  • Efficacy
  • Pediatric

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  • Yu Zhi Chen

  • William W. Busse

  • Søren Pedersen

  • Wan Tan

  • Carl Johan Lamm

  • Paul M. O'Byrne

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