Effect of antiadhesive agents on peritoneal carcinomatosis in an experimental model

  • Pucciarelli S
  • Codello L
  • Rosato A
 et al. 
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Abstract

Auto-crosslinked polysaccharide hyaluronan-based solution (Hyalobarrier-gel) prevents postoperative adhesions. However, its effect on tumour growth is still unknown. The aim of the present study was therefore to investigate the impact on survival of intra-abdominally administered Hyalobarrier-gel, native hyaluronan (HA) and hyaluronan/carboxymethylcellulose (HA/CMC), after intraperitoneal tumour implantation.

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