Effect of intra-arterial cisplatin on multiple liver metastases from rectal cancer associated with ulcerative colitis

  • C. S
  • X.-J. J
  • Y. F
 et al. 
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We report a patient with synchronous multiple liver metastases from rectal cancer associated with ulcerative colitis. Because the liver tumors were unresectable, we performed total proctocolectomy and hepatic intra-arterial cisplatin infusion with systemic oral administration of fluorouracil. A complete response was obtained. The patient is alive without sign of recurrence 5 years postoperatively. Hepatic intra-arterial administration of cisplatin should be considered in the treatment of unresectable liver metastases from colorectal cancer. © 2004 Tohoku University Medical Press.

Author-supplied keywords

  • *cisplatin/ad [Drug Administration]
  • *cisplatin/ae [Adverse Drug Reaction]
  • *cisplatin/cb [Drug Combination]
  • *cisplatin/dt [Drug Therapy]
  • *cisplatin/ia [Intraarterial Drug Administration]
  • *cisplatin/iv [Intravenous Drug Administration]
  • *cisplatin/pd [Pharmacology]
  • *liver metastasis/dt [Drug Therapy]
  • *rectum cancer/su [Surgery]
  • *ulcerative colitis
  • adult
  • article
  • cancer recurrence
  • case report
  • computer assisted tomography
  • disease association
  • drug efficacy
  • drug response
  • fluorouracil/cb [Drug Combination]
  • fluorouracil/dt [Drug Therapy]
  • fluorouracil/iv [Intravenous Drug Administration]
  • fluorouracil/po [Oral Drug Administration]
  • hepatic artery
  • human
  • human tissue
  • ileostomy
  • liver dysfunction/si [Side Effect]
  • lymph node metastasis
  • male
  • postoperative period
  • proctocolectomy

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  • Shibata C.

  • Jin X.-J.

  • Funayama Y.

  • Fukushima K.

  • Takahashi K.-I.

  • Hashimoto A.

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