Effect of intra-arterial cisplatin on multiple liver metastases from rectal cancer associated with ulcerative colitis

  • Shibata C
  • Jin X
  • Funayama Y
 et al. 
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Abstract

We report a patient with synchronous multiple liver metastases from rectal cancer associated with ulcerative colitis. Because the liver tumors were unresectable, we performed total proctocolectomy and hepatic intra-arterial cisplatin infusion with systemic oral administration of fluorouracil. A complete response was obtained. The patient is alive without sign of recurrence 5 years postoperatively. Hepatic intra-arterial administration of cisplatin should be considered in the treatment of unresectable liver metastases from colorectal cancer. © 2004 Tohoku University Medical Press.

Author-supplied keywords

  • Cisplatin
  • Colitic cancer
  • Liver
  • Metastasis
  • Ulcerative colitis

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Authors

  • C Shibata

  • X.-J. Jin

  • Y Funayama

  • K Fukushima

  • K.-I. Takahashi

  • A Hashimoto

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