The effect of two levels of pressure support ventilation on tidal volume delivery and minute ventilation in preterm infants

  • Gupta S
  • Sinha S
  • Donn S
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Abstract

OBJECTIVE: To study the effect of different levels of pressure support ventilation (PSV) on respiratory parameters in preterm infants during the weaning phase of mechanical ventilation. Design/methods: In this quasi-experimental crossover study, a total of 19 154 breaths were analysed from 10 ventilated infants of
RESULTS: The addition of full PSV (PS(max)) was associated with a significant increase in total minute ventilation as compared with SIMV alone (392 ml/kg/min vs 270 ml/kg/min, respectively; p
CONCLUSIONS: Pressure support ventilation increases total minute ventilation and stabilises breathing in proportion to the level of pressure support used. This may be advantageous and provide a useful ventilation strategy for use during weaning stages of mechanical ventilation in preterm infants.

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Authors

  • S. Gupta

  • S. K. Sinha

  • S. M. Donn

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