Obesity and impaired glucose tolerance are associated with a greater risk for a number of conditions, including insulin resistance, diabetes mellitus, hypertension, dyslipidemia, coagulation abnormalities, inflammatory markers, and coronary heart disease. Lifestyle changes can delay or prevent the development of type 2 diabetes in patients with obesity and impaired glucose tolerance. The risks improve with weight loss and increased physical activity. A decrease of 7% to 10% or more from baseline weight can have a significant effect. This has now been documented in a number of randomized, controlled studies. © 2007 International Life Sciences Institute.
CITATION STYLE
Pi-Sunyer, F. X. (2007, March). How effective are lifestyle changes in the prevention of type 2 diabetes mellitus? Nutrition Reviews. https://doi.org/10.1301/nr.2007.mar.101-110
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