Effects of anti-diabetic drugs on bone metabolism

Abstract

An increased fracture risk is observed in Type 1 and Type 2 diabetic patients. Although diabetes-related complications are important in the etiology of bone fracture in diabetes, the effect of anti-diabetic medications should not be neglected. Indeed, many drugs used commonly to treat diabetes can interfere with bone physiology, resulting in a positive or negative impact on skeletal health. The aim of the present review is to summarize the current evidence on the effects of anti-diabetic drugs on bone.