Effects of captopril on ischemic events after myocardial infarction: Results of the survival and ventricular enlargement trial

  • Rutherford J
  • Pfeffer M
  • Moyé L
 et al. 
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Abstract

Background In the Survival and Ventricular Enlargement (SAVE) trial, recurrent myocardial infarction (MI) was the most important predictor of a poor outcome and conferred a sevenfold increase in risk of death. The purpose of this study was to determine the predictors of recurrent MI in study participants and to examine the influence of the angiotensin- converting enzyme inhibitor captopril on this and other myo- cardial ischemic events. Methods and Results The 2231 patients had survived the acute phase of MI (3 to 16 days) and had a radionuclide ventricular ejection fraction

Author-supplied keywords

  • angioplasty
  • bypass
  • captopril
  • ischemia
  • myocardial infarction

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Authors

  • John D. Rutherford

  • Marc A. Pfeffer

  • Lemuel A. Moyé

  • Barry R. Davis

  • Greg C. Flaker

  • Peter R. Kowey

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