Effects of carazolol on plasma Malondialdehyde, Superoxide Dismutase and Catalase in sheeps

  • Aydin H
  • Gunduz M
  • Yardibi H
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The study was conducted to determine the effects of β-receptor blocker (carazolol) on the main detoxifying enzymes, superoxide dismutase (SOD) and catalase (CAT), in sheep. 12 Kivircik sheep were divided into two groups of six animals each and treated with 1 ml physiologic serum/ewe (group 1; control) and 0.5 mg carazolol/ewe injected i.m. (group 2; treatment). After the treatment, blood samples were collected at 24, 48 and 72 h. Results revealed that there were no differences observed in antioxidant enzyme values in sheep plasma. Oxidative stress marker was also unaffected by carazolol. It is suggested that carazolol can be alternatively used as a β-blocker agent in sheep.

Author-supplied keywords

  • Antioxidant status
  • Carazolol
  • Catalase
  • Dissmutase
  • Plasma
  • Sheep
  • Superoxide

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  • SGR: 67650576003
  • PUI: 354929793
  • SCOPUS: 2-s2.0-67650576003
  • ISSN: 16805593


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