Effects of low oxygen saturation limits on the ductus arteriosus in extremely low birth weight infants

  • Noori S
  • Patel D
  • Friedlich P
 et al. 
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Abstract

Objective: Postnatal increase in oxygen promotes constriction of the patent ductus arteriosus (PDA). According to the findings of prospective observational studies, the clinical practice of targeting lower fractional oxygen saturation between 70 and 90% has been associated with a reduced incidence of severe retinopathy of prematurity (ROP) without affecting survival or neurodevelopmental disability at 1 year of age. Our objective was to investigate the impact of the use of a lower oxygen saturation target range on the incidence of early hemodynamically significant PDA (hsPDA) and the need for ductal ligation in extremely low birth weight (ELBW,

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Authors

  • Istvan SeriSemmelweis University Faculty of Medicine

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  • S. Noori

  • D. Patel

  • P. Friedlich

  • B. Siassi

  • R. Ramanathan

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