Efficacy and tolerability of pregabalin as preventive treatment for migraine: A 3-month follow-up study

  • Pizzolato R
  • Villani V
  • Prosperini L
 et al. 
  • 13

    Readers

    Mendeley users who have this article in their library.
  • 18

    Citations

    Citations of this article.

Abstract

Migraine is a common neurological disorder and epidemiological studies have documented its high social and economic impact. Unfortunately, preventive treatment is often insufficient to substantially reduce migraine frequency or it is not well tolerated. Antiepileptic drugs are increasingly used in migraine prevention. However, data on efficacy and tolerability of pregabalin in patients with migraine are still lacking. Our aim was to evaluate efficacy and tolerability of pregabalin in patients with migraine. We recruited 47 patients who started pregabalin at 75 mg/day, which was titrated to 300 mg/day as tolerated. A total of six patients (13%) reported one or more side effects during the intake of pregabalin; however, three of them discontinued pregabalin, because side effects were intolerable and persistent. Statistically significant reduction in migraine frequency compared to baseline (p 

Author-supplied keywords

  • Disability
  • Migraine
  • Pregabalin
  • Prophylaxis therapy

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Raffaella Pizzolato

  • Veronica Villani

  • Luca Prosperini

  • Alessandro Ciuffoli

  • Giuliano Sette

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free